ScienceInsider has an update on the review of gain-of-function (GOF) research currently underway at the National Institutes of Health (NIH). The moratorium was announced last October and is supposed to last for one year. It covers federal funding for research that would make influenza, MERS or SARS viruses more virulent or easier to transmit.
Reportedly the agency is close to signing a contract with a private company for a risk-benefit analysis. But, as you might expect with any restriction imposed on active scientific research, there is concern about what NIH has been doing. Two researchers, Sir Richard Roberts and David Relman, sent the Chairman of the National Science Advisory Board on Biosecurity a letter expressing their concerns over the process by which the pause and review have been conducted. They would prefer a more open, Asilomar-style conference where scientists and other experts in the area of gain-of-function research would meet to discuss issues and develop a set of guidelines to influence research moving forward. They are concerned about what appears to be a lack of transparency to the process, limited (if any) opportunities for public input, possible conflicts of interest (the NIH funds much GOF), a lack of risk assessment experience in the Board, and a very U.S.-centric focus.